Products from RevMAb Biosciences
RevMAb Biosciences, Inc. is a biotechnology company focused on the development of recombinant monoclonal antibodies using a revolutionary technology that does not require cell fusion and hybridoma generation. The mission of the company from San Francisco, California is to promote personal health by accelerating biomedical research and advancing disease diagnosis. RevMAb seeks to accomplish this by providing superior monoclonal antibodies to customers in research and diagnostic fields.
More information at: www.adipogen.com/revmab-biosciences
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Anti-MerTK (human), Rabbit Monoclonal (RM506)
Item number: REV-31-1398-00-R100
MerTK is a transmembrane receptor tyrosine kinase (RTK) that is mainly expressed in dendritic cells (DCs) and macrophages. It is a member of the TYRO3/AXL/MER (TAM) receptor kinase family, which also includes TYRO3 and AXL. MerTK plays a role in a number of important biological processes, including phagocytosis,...
| Keywords: | Anti-MER, Anti-MERTK, EC=2.7.10.1, Anti-Proto-oncogene c-Mer, Anti-Tyrosine-protein kinase Mer, Anti-Receptor tyrosine... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
483.00€
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Anti-UP2 (Uroplakin-2) (human), Rabbit Monoclonal (RM507)
Item number: REV-31-1399-00-R100
The protein components of uroplaques are composed of uroplakins (UPs), which are a family of transmembrane proteins, including UPIa (27 kDa), UPIb (28 kDa), UPII (15 kDa), and UPIIIa (47 kDa). UPs are exclusively expressed in the normal urothelium and are undetectable in non-urothelial tissues. They are usually...
| Keywords: | Anti-UP2, Anti-UPK2, Anti-UPII, Anti-Uroplakin-2, Anti-Uroplakin II |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
483.00€
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5-Methylcytosine (5-mC) DNA Matched Antibody Pair
Item number: REV-31-1110-MK-KI01
5-Methylcytosine is a methylated form of the DNA base cytosine that regulates gene transcription and is involved in epigenetics. It is one of the best known epigenetic modifications. This methylation typically occurs at cytosine in CpG dinucleotides in vertebrates. When cytosine is methylated, the DNA maintains the...
| Keywords: | 5-mC |
| Application: | ELISA |
| Species reactivity: | broad |
826.00€
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5-Hydroxymethylcytosine (5-hmC) DNA Matched Antibody Pair
Item number: REV-31-1111-MK-KI01
5-Hydroxymethylcytosine (5hmC) is the first oxidative product in the active demethylation of 5-methylcytosine (5mC). It not only marks active demethylation but also serves as a relatively stable DNA mark that plays distinct epigenetic roles. It is potentially important in epigenetics, because the hydroxymethyl group...
| Keywords: | 5-hmC |
| Application: | ELISA |
| Species reactivity: | broad |
826.00€
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Anti-5-Carboxylcytosine (5-caC), Rabbit Monoclonal (RM462)
Item number: REV-31-1354-00-C050
5-Carboxylcytosine (5-caC) is a recently discovered modification of DNA. Just as 5-hydroxymethylcytosine (5-hmC) is generated when the Tet family of cytosine oxygenase enzymes converts 5-methylcytosine (5-mC), it has been shown that continued activity of the Tet proteins on hydroxymethylcytosine will generate...
| Keywords: | 5-caC |
| Application: | ELISA, DB |
| Host: | Rabbit |
| Species reactivity: | broad |
631.00€
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5-Carboxylcytosine (5-caC) DNA Matched Antibody Pair
Item number: REV-31-1354-MK-KI01
5-Carboxylcytosine (5-caC) is a recently discovered modification of DNA. Just as 5-hydroxymethylcytosine (5-hmC) is generated when the Tet family of cytosine oxygenase enzymes converts 5-methylcytosine (5-mC), it has been shown that continued activity of the Tet proteins on hydroxymethylcytosine will generate...
| Keywords: | 5-caC |
| Application: | ELISA |
| Species reactivity: | broad |
826.00€
*
Anti-cAMP, Rabbit Monoclonal (RM466)
Item number: REV-31-1358-00-C050
Cyclic adenosine monophosphate or cAMP is an intracellular by-product of ATP by adenylene cyclase when G-protein Coupled Receptors (GPCR) bind various ligands on the cell surface. Cyclic AMP acts as a second messenger for signal transduction across the cell membrane and is a part of kinase activation. It regulates...
| Keywords: | Cyclic Adenosine Monophosphate |
| Application: | ELISA |
| Host: | Rabbit |
| Species reactivity: | broad |
514.00€
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Anti-cGMP, Rabbit Monoclonal (RM467)
Item number: REV-31-1359-00-C050
Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP....
| Keywords: | Cyclic Guanosine Monophosphate |
| Application: | ELISA |
| Host: | Rabbit |
| Species reactivity: | broad |
514.00€
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Anti-INI1 (SNF5/SMARCB1), Rabbit Monoclonal (RM468)
Item number: REV-31-1360-00-R100
INI1 (also known as SNF5 or SMARCB1) is a protein that is involved in the regulation of transcription, replication, and repair of DNA. It is a subunit of the SWI/SNF chromatin remodeling complex, which helps to open up DNA so that genes can be transcribed. INI1 is also involved in the repair of DNA damage, and it...
| Keywords: | Anti-hSNF5, Anti-BAF47, Anti-SMARCB1, Anti-SNF5 homolog, Anti-BRG1-associated factor 47, Anti-Integrase interactor 1... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
483.00€
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Anti-MerTK (mouse), Rabbit Monoclonal (RM469)
Item number: REV-31-1361-00-R100
MerTK is a transmembrane receptor tyrosine kinase (RTK) that is mainly expressed in dendritic cells (DCs) and macrophages. It is a member of the TYRO3/AXL/MER (TAM) receptor kinase family, which also includes TYRO3 and AXL. MerTK plays a role in a number of important biological processes, including phagocytosis,...
| Keywords: | Anti-Mer, Anti-Mertk, EC=2.7.10.1, Anti-Proto-oncogene c-Mer, Anti-Tyrosine-protein kinase Mer, Anti-Receptor tyrosine... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | mouse |
483.00€
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Anti-p44 MAPK (Erk1), Rabbit Monoclonal (RM470)
Item number: REV-31-1362-00-R100
Extracellular signal-regulated kinases 1 and 2 (also known as ERK1/2, p44/42, or MAPK3/1) belong to a family of conserved serine/threonine protein kinases known as mitogen-activated protein kinases (MAPKs) that are involved in many cellular programs such as proliferation, differentiation, motility and survival. The...
| Keywords: | Anti-ERT2, Anti-ERK1, Anti-MAPK3, Anti-ERK-1, Anti-MAPK 3, Anti-p44-ERK1, Anti-p44-MAPK, EC=2.7.11.24, Anti-MAP kinase 3,... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
483.00€
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Anti-CD137 (4-1BB), Rabbit Monoclonal (RM471)
Item number: REV-31-1363-00-R100
CD137 is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation,...
| Keywords: | Anti-CD137, Anti-CDw137, Anti-TNFRSF9, Anti-T-cell antigen ILA, Anti-4-1BB ligand receptor, Anti-T-cell antigen 4-1BB... |
| Application: | FACS, IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
483.00€
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