Curing HIV/AIDS is still one of the great medical challenges of our time - but now, for the first time, there might be a chance to eradicate the deadly virus worldwide! And the origin of this incredible medical breakthrough lies nowhere other than in Hamburg, Biomol's hometown!
The best-known variant of "lipid-based drug delivery systems" is the so-called lipid nanoparticle. In the second part of our LBDDS blog series, we will first provide an overview of the developmental history of LNPs and the "endosomal escape" – a crucial point in the transport pathway of LNPs. We will then go into the potential medical applications of LNPs – all the way to SARS-CoV-2 vaccination!
One year celebrating the most exciting stories in science history.
On February 12, 1941 penicillin was first used in the treatment of a patient. This was the first time that an effective drug for the treatment of bacterial infections became available.
65 years ago the first immortalized cell line, today known as HeLa, was established.
On January 6, 1971 Berkeley chemists announced the first synthetic production of growth hormone.
On September 14, 1990, Ashanti DeSilva became the first of only two participants in the world's first approved gene therapy trial.
This new chapter of our Science History series takes us only a few years back to one of the more recent discoveries in the field of cell biology and embryology.
On August 7, 1975, César Milstein and Georges Köhler published their seminal paper on the production of monoclonal antibodies in continuous cell culture.
On July 27, 1921, Sir Frederick Banting and Charles Best succeeded in isolating insulin from canine pancreases and thereby discovered the first effective treatment for diabetes mellitus
On June 27, 1976 Y.G., a storekeeper at the cotton factory in South Sudan, suddenly became ill with a high fever, chest pain, and headache. This disease would later be named after the Ebola River.
On June 5, 1981, Michael S. Gottlieb and Joel Weisman jointly reported an unusual and novel immunological condition in homosexual men. They termed the new disease Gay-Related Immune Deficiency (GRID); it would later be renamed AIDS.