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Item number: A500-001A-T
Protein function: Regulates cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1). Inhibition of mTORC1 is mediated by a pathway that involves DDIT4/REDD1, AKT1, the TSC1-TSC2 complex and the GTPase RHEB. Plays an important role in responses to...
| Keywords: | Anti-REDD1, Anti-DDIT4, Anti-REDD-1, Anti-HIF-1 responsive protein RTP801, Anti-DNA damage-inducible transcript 4 protein,... |
| Application: | WB, IP, ICC |
| Host: | Mouse |
| Species reactivity: | human |
From 172.00€
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Item number: A500-007A-T
Protein function: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. [The UniProt Consortium]
| Keywords: | Anti-APOH, Anti-B2G1, Anti-Apo-H, Anti-B2GPI, Anti-Beta(2)GPI, Anti-APC inhibitor, Anti-Apolipoprotein H,... |
| Application: | WB, IP |
| Host: | Mouse |
| Species reactivity: | human |
From 172.00€
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Item number: A500-009A-T
Protein function: Probable RNA helicase. Required for miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA- mediated cleavage of complementary mRNAs by RISC. [The UniProt Consortium]
| Keywords: | Anti-MOV10, Anti-KIAA1631, EC=3.6.4.13, Anti-Armitage homolog, Anti-Putative helicase MOV-10, Anti-Moloney leukemia virus... |
| Application: | WB, IP, IHC |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 172.00€
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Item number: A500-010A-T
Protein function: Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation. [The UniProt Consortium]
| Keywords: | Anti-CIP2A, Anti-KIAA1524, Anti-Protein CIP2A, Anti-p90 autoantigen, Anti-Cancerous inhibitor of PP2A |
| Application: | WB, IP |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 172.00€
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Item number: A500-011A-T
Protein function: Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1...
| Keywords: | Anti-HNRPM, Anti-HNRNPM, Anti-hnRNP M, Anti-Heterogeneous nuclear ribonucleoprotein M |
| Application: | WB, IP |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 172.00€
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Item number: A500-012A-T
Protein function: RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields...
| Keywords: | Anti-IMP2, Anti-IMP-2, Anti-IGF2BP2, Anti-VICKZ family member 2, Anti-IGF2 mRNA-binding protein 2, Anti-IGF-II... |
| Application: | WB, IP |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 172.00€
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Item number: A500-013A-T
Protein function: RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields...
| Keywords: | Anti-IMP2, Anti-IMP-2, Anti-IGF2BP2, Anti-VICKZ family member 2, Anti-IGF2 mRNA-binding protein 2, Anti-IGF-II... |
| Application: | WB, IP |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 172.00€
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Item number: A500-014A-T
Protein function: May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [The UniProt Consortium]
| Keywords: | Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein |
| Application: | WB, IP |
| Host: | Mouse |
| Species reactivity: | human |
From 172.00€
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Item number: A500-015A-T
Protein function: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this...
| Keywords: | Anti-P53, Anti-TP53, Anti-Antigen NY-CO-13, Anti-Phosphoprotein p53, Anti-Tumor suppressor p53, Anti-Cellular tumor... |
| Application: | WB, IP, IHC, FC |
| Host: | Mouse |
| Species reactivity: | human |
From 172.00€
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Item number: A500-017A-T
Protein function: This protein may be involved in the regulation of B-cell activation and proliferation. [The UniProt Consortium]
| Keywords: | Anti-Bp35, Anti-CD20, Anti-MS4A1, Anti-B-lymphocyte antigen CD20, Anti-B-lymphocyte surface antigen B1, Anti-Leukocyte... |
| Application: | WB, IHC, IHC-IF, FC, MIF |
| Host: | Mouse |
| Species reactivity: | human |
From 172.00€
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Item number: A500-018A-T
Protein function: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid...
| Keywords: | Anti-CD68, Anti-Gp110, Anti-Macrosialin |
| Application: | IHC, IHC-IF, FC, MIF |
| Host: | Mouse |
| Species reactivity: | human |
From 172.00€
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Item number: A500-019A-T
| Application: | IHC, IHC-IF, ICC-IF, MIF |
| Host: | Mouse |
| Species reactivity: | human |
From 172.00€
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