Wntless (human recombinant)

Wntless (human recombinant)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-32-5251-10 10 µg - -

3 - 11 business days*

554.00€
 
Source : E.coli. WLS Human Recombinant produced in E.Coli is a single, non-glycosylated... more
Product information "Wntless (human recombinant)"
Source : E.coli. WLS Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 155 amino acids (101-232a.a) and having a molecular mass of 17.8kDa. WLS is fused to a 23 amino acid His-tag at N-terminus , purified by proprietary chromatographic techniques. WLS (Wnt trafficking regulator) is a multipass transmembrane protein which regulates the sorting and secretion of Wnt protein. WLS is necessitated for organogenesis during embryogenesis and for the establishment of the anterior-posterior axis. WLS is encoded by a gene which maps to human chromosome 1 and is expressed as multiple alternatively spliced isoforms. WLS promotes various cancers such as glioma tumourigenesis. Protein function: Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. [The UniProt Consortium]
Keywords: EVI, WLS, C1orf139, Protein wntless homolog, Integral membrane protein GPR177, Protein evenness interrupted homolog, Putative NF-kappa-B-activating protein 373
Supplier: Abeomics
Supplier-Nr: 32-5251

Properties

Conjugate: No
Format: Solution

Database Information

UniProt ID : Q5T9L3 | Matching products
Gene ID GeneID 79971 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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