Uridine Monophosphate Kinase 2, Recombinant, Human, aa1-228, His-tag (UMPK, CMPK1, Uridine-Cytidine

Uridine Monophosphate Kinase 2, Recombinant, Human, aa1-228, His-tag (UMPK, CMPK1, Uridine-Cytidine
Item number Size Datasheet Manual SDS Delivery time Quantity Price
U2281-05.100 100 µg - -

1 - 19 business days

519.00€
 
CMPK1, also known as UMP-CMP kinase and deoxycytidylate kinase, is an enzyme that catalyzes the... more
Product information "Uridine Monophosphate Kinase 2, Recombinant, Human, aa1-228, His-tag (UMPK, CMPK1, Uridine-Cytidine"
CMPK1, also known as UMP-CMP kinase and deoxycytidylate kinase, is an enzyme that catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction leads to the formation of ADP and the corresponding nucleoside diphosphate, which are required for cellular nucleic acid synthesis. It also plays an important role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. Description: E. coli-expressed recombinant protein corresponding to aa1-228 of human CMPK1 (NCBI Accession # NP_057392) fused to His-tag at the N-terminus. AA Sequence: MGSSHHHHHH SSGLVPRGSH MLSRCRSGLL HVLGLSFLLQ TRRPILLCSP RLMKPLVVFV LGGPGAGKGT QCARIVEKYG YTHLSAGELL RDERKNPDSQ YGELIEKYIK EGKIVPVEIT ISLLKREMDQ TMAANAQKNK FLIDGFPRNQ DNLQGWNKTM DGKADVSFVL FFDCNNEICI ERCLERGKSS GRSDDNRESL EKRIQTYLQS TKPIIDLYEE MGKVKKIDAS KSVDEVFDEV VQIFDKEG, Molecular Weight: ~28kD (248aa), confirmed by MALDI-TOF, Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: CMK, UMP/CMPK, EC=2.7.4.14, UMP/CMP kinase, UMP-CMP kinase, Cytidylate kinase, Deoxycytidylate kinase, Uridine monophosphate kinase, Cytidine monophosphate kinase, Uridine monophosphate/cytidine monophosphate kinase
Supplier: United States Biological
Supplier-Nr: U2281-05

Properties

Conjugate: No
MW: 28 kD
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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