Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.) (untagged)

Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.) (untagged)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
SBB-CE0011-C050 50 µg - -

3 - 9 business days*

396.00€
 
UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer... more
Product information "Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.) (untagged)"
UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an ATP-dependent mechanism where ATP is hydrolyzed to AMP and PPi, a ubiquitin C-terminal adenylate intermediate is formed, then transferred to the E1's active site cysteine through a thioester bond. This thioester is then transferable to an E2 conjugating enzyme's active site cysteine.
Keywords: Ubiquitin E1 Enzyme, Ubiquitin-like Modifier-activating Enzyme 1, A1S9T, AMCX1, GXP1, POC20, SMAX2
Supplier: South Bay Bio
Supplier-Nr: CE0011

Properties

Application: Assays
Conjugate: No
Host: Insect cells
Species reactivity: human
MW: 118 kD
Purity: >95%
Format: Liquid

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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