UbcH5a [UBE2D1] (human) (rec.) (untagged)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
SBB-CE0021-C100	100 µg		-	-	3 - 9 business days*		396.00€

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UBE2D1 (UbcH5a) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to... more

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Product information "UbcH5a [UBE2D1] (human) (rec.) (untagged)"

UBE2D1 (UbcH5a) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D1 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D1-Ub thioester. UBE2D1 is capable of associating with numerous known E3 ligases which target abnormal proteins for proteasomal degradation through polyubiquitination. UBE2D1 is also known to interact with Parkin and to be involved in PINK1 mediated mitophagy.

Keywords:	Ubiquitin-conjugating Enzyme H5a, PUBC1, UBC5A, Ubiquitin-protein Ligase D1, p53-regulated Ubiquitin-conjugating Enzyme 1
Supplier:	South Bay Bio
Supplier-Nr:	CE0021

Properties

Application:	Assays
Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	17 kD
Purity:	>95%
Format:	Liquid

Database Information

KEGG ID :	K06689 \| Matching products
UniProt ID :	P51668 \| Matching products
Gene ID	GeneID 7321 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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