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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH033168.10 | 10 µg | - |
7 - 16 business days* |
139.00€
|
|||
E-PKSH033168.50 | 50 µg | - |
7 - 16 business days* |
352.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: Recombinant Human TNF-related Weak Inducer of Apoptosis Receptor is... more
Product information "TWEAK Receptor/TWEAK R/TNFRSF12A Protein(C-Fc) (recombinant human)"
Protein Construction: Recombinant Human TNF-related Weak Inducer of Apoptosis Receptor is produced by our Mammalian expression system and the target gene encoding Glu28-Trp79 is expressed with a Fc tag at the C-terminus. Sequence: Glu28-Trp79. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 35 kDa. Protein function: Tumor necrosis factor receptor superfamily member 12A(TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor. TNFRSF12A is a single-pass type I membrane protein, including a 27 aa signal peptide, a 53 aa extracellular domain, a 21 aa transmembrane domain and a 28 aa cytoplasmic domain. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A can be induced by FGF1 and phorbol ester. TNFRSF12A binds to TWEAK/TNFSF12A to initiate a signal transduction cascade, causing different cellular responses such as cell death, cell proliferation, and angiogenesis. Protein function: Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. [The UniProt Consortium]
Keywords: | FN14, CD266, TweakR, TNFRSF12A, Tweak-receptor, FGF-inducible 14, Tumor necrosis factor receptor superfamily member 12A, Fibroblast growth factor-inducible immediate-early response protein 14, Recombinant Human TWEAK Receptor/TWEAK R/TNFRSF12A Protein(C-F |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH033168 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | 35.6 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K05149 | Matching products |
UniProt ID : | Q9NP84 | Matching products |
Gene ID | GeneID 51330 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | +4°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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