Tropomyosin 4, Recombinant, Human, aa1-248, His-tag (TPM4, TM4)

Tropomyosin 4, Recombinant, Human, aa1-248, His-tag (TPM4, TM4)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T8664-59A.50 50 µg - -

1 - 19 business days

451.00€
 
TPM4 belongs to the tropomyosin family. Tropomyosins are present in virtually all eukaryotic... more
Product information "Tropomyosin 4, Recombinant, Human, aa1-248, His-tag (TPM4, TM4)"
TPM4 belongs to the tropomyosin family. Tropomyosins are present in virtually all eukaryotic cells (both muscle and nonmuscle), where they bind actin filaments and function to modulate actin-myosin interaction and stabilize actin filament structure. TPM4 binds to actin filaments in muscle and nonmuscle cells and plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. Source: Recombinant corresponding to aa1-248 from human TPM4, fused to His-tag at N-terminus expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAGLNSLEAV KRKIQALQQQ ADEAEDRAQG LQRELDGERE RREKAEGDVA ALNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRAMK DEEKMEIQEM QLKEAKHIAE EADRKYEEVA RKLVILEGEL ERAEERAEVS ELKCGDLEEE LKNVTNNLKS LEAASEKYSE KEDKYEEEIK LLSDKLKEAE TRAEFAERTV AKLEKTIDDL EEKLAQAKEE NVGLHQTLDQ TLNELNCI , Molecular Weight: ~30.7kD (268aa), confirmed by MALDI-TOF , Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: TM30p1, Tropomyosin-4, Tropomyosin alpha-4 chain
Supplier: United States Biological
Supplier-Nr: T8664-59A

Properties

Conjugate: No
MW: 30,7 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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