Product information "Tropomyosin 4, Recombinant, Human, aa1-248, His-tag (TPM4, TM4)"
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium. [The UniProt Consortium]