TNFRSF11B PrEST Antigen

TNFRSF11B PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST95729.100 100 µl

7 - 10 business days*

264.00€
 
PrEST Antigen TNFRSF11B, Gene description: TNF receptor superfamily member 11b, Alternative Gene... more
Product information "TNFRSF11B PrEST Antigen"
PrEST Antigen TNFRSF11B, Gene description: TNF receptor superfamily member 11b, Alternative Gene Names: OCIF, OPG, TR1, Antigen sequence: SSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTFEQLRSLMESLPGKKVGAEDIE, Storage: Upon delivery store at -20°C. Avoid repeated freeze/thaw cycles. Protein function: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis. [The UniProt Consortium] Mouse gene identity: 81% Rat gene identity: 81%
Keywords: OCIF, TNFRSF11B, Osteoprotegerin, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B
Supplier: Atlas Antibodies
Supplier-Nr: APrEST95729

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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