Speckle-type POZ Protein (SPOP) Recombinant, Human, aa1-374, His-tag

Speckle-type POZ Protein (SPOP) Recombinant, Human, aa1-374, His-tag
Item number Size Datasheet Manual SDS Delivery time Quantity Price
S5373-02.50 50 µg - -

1 - 19 business days

519.00€
 
SPOP (speckle-type POZ protein), also known as TEF2, is a member of the Tdpoz family containing... more
Product information "Speckle-type POZ Protein (SPOP) Recombinant, Human, aa1-374, His-tag"
SPOP (speckle-type POZ protein), also known as TEF2, is a member of the Tdpoz family containing one N-terminal MATH (Meprin and TRAF homology) domain and one C-terminal BTB/POZ domain. This protein inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex. Through an interaction with CUL-3, SPOP is involved in ubiquitinylation and protein degradation. Source: Recombinant corresponding to aa1-374 from human SPOP, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSRVPSPPPP AEMSSGPVAE SWCYTQIKVV KFSYMWTINN FSFCREEMGE VIKSSTFSSG ANDKLKWCLR VNPKGLDEES KDYLSLYLLL VSCPKSEVRA KFKFSILNAK GEETKAMESQ RAYRFVQGKD WGFKKFIRRD FLLDEANGLL PDDKLTLFCE VSVVQDSVNI SGQNTMNMVK VPECRLADEL GGLWENSRFT DCCLCVAGQE FQAHKAILAA RSPVFSAMFE HEMEESKKNR VEINDVEPEV FKEMMCFIYT GKAPNLDKMA DDLLAAADKY ALERLKVMCE DALCSNLSVE NAAEILILAD LHSADQLKTQ AVDFINYHAS DVLETSGWKS MVVSHPHLVA EAYRSLASAQ CPFLGPPRKR LKQS, Molecular Weight: ~44.3kD (394aa), confirmed by MALDI-TOF, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: HIB homolog 1, Roadkill homolog 1, Speckle-type POZ protein
Supplier: United States Biological
Supplier-Nr: S5373-02

Properties

Conjugate: No
MW: 44,3 kD
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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