RNMT Recombinant, Human aa1-476, His-tag (mRNA Cap Guanine-N7 Methyltransferase, mRNA (guanine-N(7

RNMT Recombinant, Human aa1-476, His-tag (mRNA Cap Guanine-N7 Methyltransferase, mRNA (guanine-N(7
Item number Size Datasheet Manual SDS Delivery time Quantity Price
R2041-70C.50 50 µg - -

1 - 19 business days

519.00€
 
RNMT (mRNA cap guanine-N7 methyltransferase), also known as MET, RG7MT1 or hCMT1c, is a widely... more
Product information "RNMT Recombinant, Human aa1-476, His-tag (mRNA Cap Guanine-N7 Methyltransferase, mRNA (guanine-N(7"
RNMT (mRNA cap guanine-N7 methyltransferase), also known as MET, RG7MT1 or hCMT1c, is a widely expressed nuclear protein that belongs to the mRNA cap methyltransferase family. Cap-dependent mRNA translation requires the methylation of the mRNA guanosine cap by RNMT. RNMT catalyzes the transfer of a methyl group from AdoMet (S-adenosylmethionine) to the GpppN end of the growing mRNA at the N-7 position, thereby producing AdoHyc (S-adenosylhomocysteine) and m7GpppN terminated RNA. Source: Recombinant corresponding to aa1-476 of human RNMT, fused with His-tag at N-terminus, expressed in E.coli. AA sequence: MGSSHHHHHH SSGLVPRGSH MANSAKAEEY EKMSLEQAKA SVNSETESSF NINENTTASG TGLSEKTSVC RQVDIARKRK EFEDDLVKES SSCGKDTPSK KRKLDPEIVP EEKDCGDAEG NSKKRKRETE DVPKDKSSTG DGTQNKRKIA LEDVPEKQKN LEEGHSSTVA AHYNELQEVG , LEKRSQSRIF YLRNFNNWMK SVLIGEFLEK VRQKKKRDIT VLDLGCGKGG DLLKWKKGRI NKLVCTDIAD VSVKQCQQRY EDMKNRRDSE YIFSAEFITA DSSKELLIDK FRDPQMCFDI CSCQFVCHYS FESYEQADMM LRNACERLSP GGYFIGTTPN SFELIRRLEA SETESFGNEI , YTVKFQKKGD YPLFGCKYDF NLEGVVDVPE FLVYFPLLNE MAKKYNMKLV YKKTFLEFYE EKIKNNENKM LLKRMQALEP YPANESSKLV SEKVDDYEHA AKYMKNSQVR LPLGTLSKSE WEATSIYLVF AFEKQQ, Molecular Weight: ~57kD (496aa), Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: EC=2.1.1.56, mRNA cap methyltransferase, mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7)-)-methyltransferase
Supplier: United States Biological
Supplier-Nr: R2041-70C

Properties

Conjugate: No
MW: 57 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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