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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-32-7037-10 | 10 µg | - | - |
3 - 11 business days* |
395.00€
|
||
ABE-32-7037-50 | 50 µg | - | - |
3 - 11 business days* |
528.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Source: E.coli. MW :17.15kD. Recombinant Mouse Fibroblast growth factor 2 is produced by our... more
Product information "Recombinant Mouse Fibroblast Growth Factor 2/FGF-2/FGFb (Met1-Ser154)"
Source: E.coli. MW :17.15kD. Recombinant Mouse Fibroblast growth factor 2 is produced by our E.coli expression system and the target gene encoding Met1-Ser154 is expressed. FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine, and sheep FGF basic. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysaccharides and lipids with lower affinity. Expression of FGF basic is nearly ubiquitous but disruption of the mouse FGF basic gene gives a relatively mild phenotype, suggesting compensation by other FGF family members. FGF basic modulates such normal processes as angiogenesis, wound healing and tissue repair, embryonic development and differentiation, neuronal function and neural degeneration. Transgenic overexpression of FGF basic results in excessive proliferation and angiogenesis is reminiscent of a variety of pathological conditions. Protein function: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Can induce angiogenesis. [The UniProt Consortium]
Supplier: | Abeomics |
Supplier-Nr: | 32-7037 |
Properties
Conjugate: | No |
Database Information
KEGG ID : | K18497 | Matching products |
UniProt ID : | P15655 | Matching products |
Gene ID | GeneID 14173 | Matching products |
Handling & Safety
Storage: | +20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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