Recombinant Human/Mouse/Rat Irisin/FNDC5 (C-Fc)

Recombinant Human/Mouse/Rat Irisin/FNDC5 (C-Fc)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-32-8703-10 10 µg - -

3 - 11 business days*

478.00€
ABE-32-8703-50 50 µg - -

3 - 11 business days*

791.00€
 
Source: Human Cells. MW :39.7kD. Recombinant Human/Mouse/Rat Irisin is produced by our Mammalian... more
Product information "Recombinant Human/Mouse/Rat Irisin/FNDC5 (C-Fc)"
Source: Human Cells. MW :39.7kD. Recombinant Human/Mouse/Rat Irisin is produced by our Mammalian expression system and the target gene encoding Asp32-Glu143 is expressed with a Fc tag at the C-terminus. FNDC5 is a membrane protein comprised by a short cytoplasmic domain, a transmembrane segment, and an ectodomain consisting of a fibronectin type III (FNIII) domain. The ectodomain has been proposed to be cleaved to a soluble peptide hormone named "irisin". Irisin is secreted from muscle in response to exercise, and may regulate energy metabolism, stem cell differentiation, and neuronal development. The circulating irisin converts white fat into the more thermogenic beige fat, and may mediate some beneficial effects of exercise in humans and the potential for generating weight loss. In mice, expression of Irisin has been shown to regulate obesity and diabetes. A similar function is suggested in human. Protein function: Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue. [The UniProt Consortium]
Supplier: Abeomics
Supplier-Nr: 32-8703

Properties

Conjugate: No

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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