Recombinant Human Prostaglandin-H2 D-Isomerase/PTGDS (C-6His)

Recombinant Human Prostaglandin-H2 D-Isomerase/PTGDS (C-6His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-32-7778-10 10 µg - -

3 - 11 business days*

403.00€
ABE-32-7778-50 50 µg - -

3 - 11 business days*

668.00€
 
Source: Human Cells. MW :19.7kD. Recombinant Human Prostaglandin-D2 Synthase is produced by our... more
Product information "Recombinant Human Prostaglandin-H2 D-Isomerase/PTGDS (C-6His)"
Source: Human Cells. MW :19.7kD. Recombinant Human Prostaglandin-D2 Synthase is produced by our Mammalian expression system and the target gene encoding Ala23-Gln190 is expressed with a 6His tag at the C-terminus. Prostaglandin-H2 D-Isomerase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS is preferentially expressed in the brain. PTGDS catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. PTGDS binds small non-substrate lipophilic molecules and may act as a scavenger for harmful hydrophopic molecules and a secretory retinoid and thyroid hormone transporter. It possibly participates in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor, blood-testis barrier, the central nervous system and male reproductive system. Protein function: Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. [The UniProt Consortium]
Supplier: Abeomics
Supplier-Nr: 32-7778

Properties

Conjugate: No

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Recombinant Human Prostaglandin-H2 D-Isomerase/PTGDS (C-6His)"
Write a review
or to review a product.
Viewed