Recombinant Human IL-1RAcP / IL-1R3 Protein (His tag)

Recombinant Human IL-1RAcP / IL-1R3 Protein (His tag)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-PKSH031857.100 100 µg -

7 - 16 business days*

539.00€
 
Protein function: Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in... more
Product information "Recombinant Human IL-1RAcP / IL-1R3 Protein (His tag)"
Protein function: Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1- dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone, binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non- signaling association with the membrane IL1R2 decoy receptor. Coreceptor for IL1RL1 in the IL-33 signaling system. Can bidirectionally induce pre- and postsynaptic differentiation of neurons by trans-synaptically binding to PTPRD. [The UniProt Consortium]
Supplier: Elabscience
Supplier-Nr: E-PKSH031857

Properties

Conjugate: No
Species reactivity: human
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Recombinant Human IL-1RAcP / IL-1R3 Protein (His tag)"
Write a review
or to review a product.
Viewed