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Recombinant Human IgG4-Fc Protein (108 Ser/Pro)

Recombinant Human IgG4-Fc Protein (108 Ser/Pro)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-PKSH030614.100 100 µg - -

7 - 16 business days

E-PKSH030614.200 200 µg - -

7 - 16 business days

Protein function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as... more
Product information "Recombinant Human IgG4-Fc Protein (108 Ser/Pro)"
Protein function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). [The UniProt Consortium]
Supplier: Elabscience
Supplier-Nr: PKSH030614


Conjugate: No
Origin: Human
Format: Lyophilized

Database Information

UniProt ID : P01861 | Search using UniProt ID

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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