PTGS2, Recombinant, Human, aa18-601, His-Tag (Prostaglandin G/H Synthase 2)

PTGS2, Recombinant, Human, aa18-601, His-Tag (Prostaglandin G/H Synthase 2)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
374921.10 10 µg - -

3 - 19 business days*

354.00€
374921.50 50 µg - -

3 - 19 business days*

472.00€
374921.100 100 µg - -

3 - 19 business days*

658.00€
374921.200 200 µg - -

3 - 19 business days*

906.00€
 
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis.... more
Product information "PTGS2, Recombinant, Human, aa18-601, His-Tag (Prostaglandin G/H Synthase 2)"
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis. Source: Recombinant protein corresponding to aa18-601 from human PTGS2, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~70.9kD, AA Sequence: ANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERS, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: COX2, PTGS2, COX-2, PHS II, PGHS-2, PGH synthase 2, Cyclooxygenase-2, Prostaglandin H2 synthase 2, Prostaglandin G/H synthase 2, Prostaglandin-endoperoxide synthase 2
Supplier: United States Biological
Supplier-Nr: 374921

Properties

Conjugate: No
MW: 70,9
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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