Protein Tyrosine Phosphatase 1B (human recombinant)

Protein Tyrosine Phosphatase 1B (human recombinant)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010896-100 100 µg -

1 - 10 business days

Protein tyrosine phosphatase (PTPs) are an enzyme superfamily that includes about 100 human... more
Product information "Protein Tyrosine Phosphatase 1B (human recombinant)"
Protein tyrosine phosphatase (PTPs) are an enzyme superfamily that includes about 100 human proteins. Their function is to remove phosphate from tyrosine residues of cellular proteins. Reversible phosphorylation catalyzed by the coordinated actions of protein tyrosine kinases and phosphatases is of paramount importance to the regulation of the signaling events that underlie such fundamental processes as growth and proliferation, differentiation, and survival or apoptosis, as well as adhesion and motility. One of the most heavily studied PTP proteins is PTP1B. Data suggests PTP1B is a negative regulator in both insulin and leptin signaling. As such, PTP1B has become a leading diabetes drug target.
Keywords: PTP1B, PTPN1, PTP-1B, EC=, Protein-tyrosine phosphatase 1B, Tyrosine-protein phosphatase non-receptor type 1
Supplier: Cayman Chemical
Supplier-Nr: 10010896-100


Application: Enzyme activity
Conjugate: No
MW: 37,3 kD
Purity: >95% estimated by SDS-PAGE
Format: Solution

Database Information

KEGG ID : K05696 | Find alternatives
UniProt ID : P18031 | Find alternatives

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H319, H335
P Phrases: P261, P264, P271, P280, P312, P304+P340, P305+P351+P338, P332+P313, P337+P313, P405, P403+P233, P501
Our products are for laboratory research use only: Not for administration to humans!
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