PPM1G, Recombinant, Human, aa1-546, His-tag (Protein Phosphatase 1G, Protein Phosphatase 1C, Protein

PPM1G, Recombinant, Human, aa1-546, His-tag (Protein Phosphatase 1G, Protein Phosphatase 1C, Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
P9107-20P.50 50 µg - -

1 - 19 business days

519.00€
 
PPM1G, as known as protein phosphatase 1G, is a member of the PP2C family of Ser/Thr protein... more
Product information "PPM1G, Recombinant, Human, aa1-546, His-tag (Protein Phosphatase 1G, Protein Phosphatase 1C, Protein"
PPM1G, as known as protein phosphatase 1G, is a member of the PP2C family of Ser/Thr protein phosphatases that is negative regulators of cell stress response pathways. This enzyme localizes to the cytoplasm and is widely expressed, with most abundant expression detected in testis, skeletal muscle and heart. It is necessary for the dephosphorylation of pre-mRNA splicing factors, which is an important process for the formation of the functional spliceosome. Purified by using conventional chromatography. Source: Recombinant corresponding to aa1-546 of human PPM1G, fused to His-tag at N-terminal, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MGAYLSQPNT VKCSGDGVGA PRLPLPYGFS AMQGWRVSME DAHNCIPELD SETAMFSVYD GHGGEEVALY CAKYLPDIIK DQKAYKEGKL QKALEDAFLA IDAKLTTEEV IKELAQIAGR PTEDEDEKEK VADEDDVDNE EAALLHEEAT MTIEELLTRY, GQNCHKGPPH SKSGGGTGEE PGSQGLNGEA GPEDSTRETP SQENGPTAKA YTGFSSNSER GTEAGQVGEP GIPTGEAGPS CSSASDKLPR VAKSKFFEDS EDESDEAEEE EEDSEECSEE EDGYSSEEAE NEEDEDDTEE AEEDDEEEEE EMMVPGMEGK EEPGSDSGTT AVVALIRGKQ, LIVANAGDSR CVVSEAGKAL DMSYDHKPED EVELARIKNA GGKVTMDGRV NGGLNLSRAI GDHFYKRNKN LPPEEQMISA LPDIKVLTLT DDHEFMVIAC DGIWNVMSSQ EVVDFIQSKI SQRDENGELR LLSSIVEELL DQCLAPDTSG DGTGCDNMTC IIICFKPRNT AELQPESGKR, KLEEVLSTEG AEENGNSDKK KKAKRD, Molecular Weight: ~61.4kD (566aa), Biological Activity: Specific activity: >3,000 units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme hydrolyzing 1 nmole of p-nitrophenyl phosphate (pNPP) per minute at 25C, pH7.5 using 10mM of substrate. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: EC=3.1.3.16, Protein phosphatase 1C, Protein phosphatase 1G, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium-dependent 1 gamma
Supplier: United States Biological
Supplier-Nr: P9107-20P

Properties

Conjugate: No
MW: 61,4 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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