PEDF, Recombinant, Human (Pigment Epithelium Derived Factor, Alpha-2-antiplasmin, EPC-1, Proliferati

PEDF, Recombinant, Human (Pigment Epithelium Derived Factor, Alpha-2-antiplasmin, EPC-1, Proliferati
Item number Size Datasheet Manual SDS Delivery time Quantity Price
P3140-02E.100 100 µg - -

3 - 19 business days*

568.00€
P3140-02E.500 500 µg - -

3 - 19 business days*

1,099.00€
 
PEDF, also known as SERPINF1, is an extracellular neurotrophic agent, first identified as a... more
Product information "PEDF, Recombinant, Human (Pigment Epithelium Derived Factor, Alpha-2-antiplasmin, EPC-1, Proliferati"
PEDF, also known as SERPINF1, is an extracellular neurotrophic agent, first identified as a secreted product in conditioned medium from cultured fetal human retinal pigment epithelial (RPE) cells. It was reported that PEDF isolated from medium conditioned by human fetal RPE primary cultures promotes neurite outgrowth in cultured human retinoblastoma Y-79 cells. PEDF is also a member of the serpin family, a group of serine protease inhibitors. As PEDF does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. Source: Recombinant PEDF protein containing a natural variant M72T was expressed in E.coli and purified by using conventional chromatography techniques. Molecular Weight: 46.7kD(420aa). AA Sequence: MGSSHHHHHH SSGLVPRGSH MQNPASPPEE GSPDPDSTGA LVEEEDPFFK VPVNKLAAAV SNFGYDLYRV RSSMSPTTNV LLSPLSVATA LSALSLGAEQ RTESIIHRAL YYDLISSPDI HGTYKELLDT VTAPQKNLKS ASRIVFEKKL RIKSSFVAPL EKSYGTRPRV LTGNPRLDLQ EINNWVQAQM KGKLARSTKE IPDEISILLL GVAHFKGQWV TKFDSRKTSL EDFYLDEERT VRVPMMSDPK AVLRYGLDSD LSCKIAQLPL TGSMSIIFFL PLKVTQNLTL IEESLTSEFI HDIDRELKTV QAVLTVPKLK LSYEGEVTKS LQEMKLQSLF DSPDFSKITG KPIKLTQVEH RAGFEWNEDG AGTTPSPGLQ PAHLTFPLDY HLNQPFIFVL RDTDTGALLF IGKILDPRGP, Storage and Stability: For long-term storage, aliquot and store at -20°C/-70°C. Aliquots are stable for at least 6 months at -20°C/-70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: PEDF, EPC-1, PIG35, SERPINF1, Serpin F1, Pigment epithelium-derived factor, Cell proliferation-inducing gene 35 protein
Supplier: United States Biological
Supplier-Nr: P3140-02E

Properties

Conjugate: No
Species reactivity: human
Format: Purified

Handling & Safety

Storage: vT
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "PEDF, Recombinant, Human (Pigment Epithelium Derived Factor, Alpha-2-antiplasmin, EPC-1, Proliferati"
Write a review
or to review a product.
Viewed