Product information "Osteocrin, Recombinant, Human, aa28-133, His-tag (OSTN, Musclin)"
Osteocrin (OSTN), also known as Musclin, contains two conserved sequence motifs homologous to the natriuretic peptide family. This protein appears to modulate osteoblastic differentiation and highly expressed in cells of osteoblast lineage and in skeletal muscle tissue. It could also function as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle. Source: Recombinant corresponding to aa28-133 from human OSTN, fused to His-tag at N-terminus expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MVDVTTTEAF DSGVIDVQST PTVREEKSAT DLTAKLLLLD ELVSLENDVI ETKKKRSFSG FGSPLDRLSA GSVDHKGKQR KVVDHPKRRF GIPMDRIGRN RLSNSRG, Molecular Weight: ~14kD (127aa) confirmed by MALDI-TOF, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.