Product information "NTH, Recombinant, Human, aa1-211, His-tag (Endonuclease III Like 1, NTHL1, OCTS3)"
Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions. [The UniProt Consortium]
b1633, EC=126.96.36.199, DNA-(apurinic or apyrimidinic site) lyase