NTH, Recombinant, Human, aa1-211, His-tag (Endonuclease III Like 1, NTHL1, OCTS3)

NTH, Recombinant, Human, aa1-211, His-tag (Endonuclease III Like 1, NTHL1, OCTS3)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E2291-41C.250 250 µg - -

1 - 19 business days

867.00€
 
Nth, also known as Endonuclease III, has an apurinic and/or apyrimidinic endonuclease activity... more
Product information "NTH, Recombinant, Human, aa1-211, His-tag (Endonuclease III Like 1, NTHL1, OCTS3)"
Nth, also known as Endonuclease III, has an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. This enzyme incises damaged DNA at cytosines, thymines and guanines. Nth acts on a damaged strand, 5' from the damaged site. This enzyme is required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions. Description: Recombinant E. coli NTH (Endonuclease III) protein fused to His-tag at the N-terminus, expressed in E. coli, AA Sequence: MGSSHHHHHH SSGLVPRGSH MNKAKRLEIL TRLRENNPHP TTELNFSSPF ELLIAVLLSA QATDVSVNKA TAKLYPVANT PAAMLELGVE GVKTYIKTIG LYNSKAENII KTCRILLEQH NGEVPEDRAA LEALPGVGRK TANVVLNTAF GWPTIAVDTH IFRVCNRTQF APGKNVEQVE EKLLKVVPAE FKVDCHHWLI LHGRYTCIAR KPRCGSCIIE DLCEYKEKVD I, Molecular Weight: 25.7kD (231aa) confirmed by MALDI-TOF, Enzyme Activity:, Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C or lower. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: b1633, EC=4.2.99.18, DNA-(apurinic or apyrimidinic site) lyase
Supplier: United States Biological
Supplier-Nr: E2291-41C

Properties

Conjugate: No
MW: 25,7 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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