Liver X receptor beta, Ligand Binding Domain (LXR beta-BDL), human recombinant, plant based, bio-cle

Produced by transient expression of LXR in non-transgenic plants. Recombinant human LXR contains a 6-His-tag at the N-terminal end and is purified by sequential chromatography (FPLC). Contains no animal-derived components or impurities. Liver X Receptors (LXRs) are nuclear receptors that regulate the metabolism of cholesterol and bile acids. There are two subtypes of LXRs LXRalpha and LXRbeta. The LXRs are ligand-dependent transcription factors that form permissive heterodimers with the retinoid X receptor (RXR). LXR- member of Nuclear Receptor Family is activated by certain oxysterol derivatives of cholesterol. They play an important role in cholesterol lipid and carbohydrate metabolism.