Leukocyte Ig-Like Receptor B1/ LILRB1/ILT2/CD85j (C-Fc) (recombinant human)

Protein Construction: Recombinant Human Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 is produced by our Mammalian expression system and the target gene encoding Gly24-His458 is expressed with a Fc tag at the C-terminus. Sequence: Gly24-His458. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 100-120 kDa. Protein function: The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR)) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR). Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes,dendritic cells,and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.