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Interferon Regulatory Factor-1, His Tag, human recombinant (rHuIRF-1-His)
Product information "Interferon Regulatory Factor-1, His Tag, human recombinant (rHuIRF-1-His)"
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 134 amino acids (1-114) with a His Tag of 20 amino acids. IRF-1 regulates gene expression critical to immune response, hematopoiesis and proliferation.