Human Omentin

Human Omentin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-32-12265-10 10 µg - -

2 - 11 business days

435.00€
ABE-32-12265-100 100 µg - -

2 - 11 business days

1,021.00€
 
Source: Genetically modified E.coli. Predicted MW: Dimer, 35.0/70.0 kDa (313/626 aa)Omentin is an... more
Product information "Human Omentin"
Source: Genetically modified E.coli. Predicted MW: Dimer, 35.0/70.0 kDa (313/626 aa)Omentin is an adipokine that is produced and secreted by the small intestine, visceral adipose tissue, perivascular adipose tissue, and epicardial adipose tissue. Omentin enhances insulin-stimulated glucose uptake in adipocytes and is a link between obesity and Type 2 Diabetes. Omentin also functions as a vasodilator and plays a protective role during coronary atherosclerosis and hypertension. Protein function: Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed:11313366, PubMed:26148048). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta- linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D- manno-oct-2-ulosonic acid (KDO) (PubMed:26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris (PubMed:26148048). Does not bind human glycans (PubMed:26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed:16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed:16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed:11747454, PubMed:23921499). [The UniProt Consortium]
Supplier: Abeomics
Supplier-Nr: 32-12265

Properties

Conjugate: No

Handling & Safety

Storage: -20°C
Shipping: °C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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