Product information "HSD17B8, Recombinant, Human, aa1-261, His-tag (FABGL, HKE6, RING2)"
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. [The UniProt Consortium]