Histone Chaperone ASF1A/ASF1A Protein(C-6His, N-T7 tag) (recombinant human)

Histone Chaperone ASF1A/ASF1A Protein(C-6His, N-T7 tag) (recombinant human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-PKSH032549.10 10 µg -

7 - 16 business days*

212.00€
E-PKSH032549.50 50 µg -

7 - 16 business days*

622.00€
 
Protein Construction: Recombinant Human Histone Chaperone ASF1A is produced by our E.coli... more
Product information "Histone Chaperone ASF1A/ASF1A Protein(C-6His, N-T7 tag) (recombinant human)"
Protein Construction: Recombinant Human Histone Chaperone ASF1A is produced by our E.coli expression system and the target gene encoding Met1-Met204 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus. Sequence: Met 1-Met204. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 22 kDa. Protein function: Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. Protein function: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. [The UniProt Consortium]
Keywords: CIA, hCIA, ASF1A, hAsf1, CGI-98, hAsf1a, Histone chaperone ASF1A, CCG1-interacting factor A, Anti-silencing function protein 1 homolog A, Recombinant Human Histone Chaperone ASF1A/ASF1A Protein(C-6His, N-T7 tag)
Supplier: Elabscience
Supplier-Nr: E-PKSH032549

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
MW: 25.4 kD
Format: Lyophilized

Handling & Safety

Storage: -80°C
Shipping: +4°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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