HDAC2, Recombinant, Human, aa1-488, His-tag (Histone Deacetylase 2, Tanscriptional Regulator Homolog

HDAC2, Recombinant, Human, aa1-488, His-tag (Histone Deacetylase 2, Tanscriptional Regulator Homolog
Item number Size Datasheet Manual SDS Delivery time Quantity Price
H1827-53E.50 50 µg - -

4 - 22 business days

519.00€
 
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones... more
Product information "HDAC2, Recombinant, Human, aa1-488, His-tag (Histone Deacetylase 2, Tanscriptional Regulator Homolog"
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. [The UniProt Consortium]
Keywords: EC=3.5.1.98, Histone deacetylase 2
Supplier-Nr: H1827-53E

Properties

MW: 56,4 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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