Galectin-7, His tag, mouse recombinant (rmLGALS7-His)

Galectin-7, His tag, mouse recombinant (rmLGALS7-His)
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
97603.5 5 µg - -

3 - 10 business days*

70.00€
97603.20 20 µg - -

3 - 10 business days*

180.00€
97603.1 1 mg - -

3 - 10 business days*

-
 
Mouse recombinant LGALS7 produced E.coli is a single polypeptide chain containing 159 amino acids... more
Product information "Galectin-7, His tag, mouse recombinant (rmLGALS7-His)"
Mouse recombinant LGALS7 produced E.coli is a single polypeptide chain containing 159 amino acids (1-136) and having a molecular mass of 17.6kDa. LGALS7 is fused to a 23 amino acid His-tag at N-terminus. Galectins are a family of animal lectins with an affinity for beta-galactosides. This family has at least 14 identified members. Galectins share similarities in the CRD (the carbohydrate recognition domain). Galectins are synthesized as cytosolic proteins. Though localized principally in the cytoplasm and lacking a classical signal peptide, galectins can also be stimulated to secretion by non-classical pathways or alternatively targeted to the nucleus. Galectins are involved in modulating cell-cell and cell-matrix interactions. Human Galectin-7 belongs to the prototypical Galectins containing a single CRD, which is initially identified in human epidermis as a monomer. The Galectin-7 expression is induced by tumor suppressor protein p53 and associated with apoptosis. Galectin-7 is a pro-apoptotic protein which functions intracellularlly upstream of JNK activation and mitochondrial cytochrome c release. The correlation of Galectin-7 with the UV-induced apoptosis of keratinocytes presents a critical mechanism in the maintenance of epidermal homeostasis. Human Galectin-7 is localized in both nucleus and cytoplasm.
Keywords: Gal-7, Lgals7, Galectin-7
Supplier: Biomol GmbH
Supplier-Nr: 97603.1

Properties

Application: Bioassays
Conjugate: No
Expressed in: E.coli
Origin: Mouse
MW: 17600 D
Purity: >95%
Format: Solution

Database Information

UniProt ID : O54974 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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