G Protein Coupled Receptor, MRGX, Recombinant, Human, aa1-288, His-tag (KIAA0026 gene product, MORF

G Protein Coupled Receptor, MRGX, Recombinant, Human, aa1-288, His-tag (KIAA0026 gene product, MORF
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G8603-09H.100 100 µg - -

4 - 22 business days

451.00€
 
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional... more
Product information "G Protein Coupled Receptor, MRGX, Recombinant, Human, aa1-288, His-tag (KIAA0026 gene product, MORF"
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones. [The UniProt Consortium]
Keywords: Protein MSL3-2, MORF-related gene X protein, Mortality factor 4-like protein 2, Transcription factor-like protein MRGX
Supplier-Nr: G8603-09H

Properties

MW: 34,4 kD
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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