Cell division cycle associated 8, Recombinant, Human, aa19-280, His-tag (BOR, Borealin, BOREALIN, Ce

Cell division cycle associated 8, Recombinant, Human, aa19-280, His-tag (BOR, Borealin, BOREALIN, Ce
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2098-69D.250 250 µg - -

1 - 19 business days

1,074.00€
 
CDCA8, also known as Borealin, is a component of the chromosomal passenger complex (CPC). The CPC... more
Product information "Cell division cycle associated 8, Recombinant, Human, aa19-280, His-tag (BOR, Borealin, BOREALIN, Ce"
CDCA8, also known as Borealin, is a component of the chromosomal passenger complex (CPC). The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 protein may be required to direct the CPC to centromeric DNA. Deletion of CDCA8 delays mitotic progression and causes kinetochore-spindle to mis-attach. Source: Recombinant corresponding to aa19-280 from human CDCA8, fused to His-tag at N-terminus expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MRKLASFLKD FDREVEIRIK QIESDRQNLL KEVDNLYNIE ILRLPKALRE MNWLDYFALG GNKQALEEAA TADLDITEIN KLTAEAIQTP LKSAKTRKVI QVDEMIVEEE EEEENERKNL QTARVKRCPP SKKRTQSIQG KGKGKRSSRA NTVTPAVGRL EVSMVKPTPG LTPRFDSRVF KTPGLRTPAA GERIYNISGN GSPLADSKEI FLTVPVGGGE SLRLLASDLQ RHSIAQLDPE ALGNIKKLSN RLAQICSSIR THK, Molecular Weight: ~31.6kD (283aa) confirmed by MALDI-TOF, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: CDCA8
Supplier: United States Biological
Supplier-Nr: C2098-69D

Properties

Conjugate: No
MW: 31,6 kD
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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