CD278 [ICOS] (human):Fc (human) (rec.)(non-lytic)

CD278 [ICOS] (human):Fc (human) (rec.)(non-lytic)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CHI-HF-220ICOS-C025 25 µg - -

3 - 9 business days*

187.00€
CHI-HF-220ICOS-C100 100 µg - -

3 - 9 business days*

396.00€
 
The extracellular domain of human CD278 [ICOS] (aa 21-139) is fused to the N-terminus of the Fc... more
Product information "CD278 [ICOS] (human):Fc (human) (rec.)(non-lytic)"
The extracellular domain of human CD278 [ICOS] (aa 21-139) is fused to the N-terminus of the Fc region of a mutant human IgG1. CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
Keywords: ICOS, Inducible T Cell Costimulator, CRP1, CD28-related Protein-1, AILIM
Supplier: Chimerigen Laboratories
Supplier-Nr: HF-220ICOS

Properties

Application: Bioassays
Conjugate: No
Expressed in: Hamster cells
Origin: Human
Purity: >98%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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