C1orf19, Recombinant, Human, aa1-171, His-tag (Chromosome 1 Open Reading Frame 19, tRNA-splicing End

C1orf19, Recombinant, Human, aa1-171, His-tag (Chromosome 1 Open Reading Frame 19, tRNA-splicing End
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C5071-19C.50 50 µg - -

4 - 22 business days

519.00€
 
Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for... more
Product information "C1orf19, Recombinant, Human, aa1-171, His-tag (Chromosome 1 Open Reading Frame 19, tRNA-splicing End"
Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events. [The UniProt Consortium]
Keywords: SEN15 homolog, tRNA-intron endonuclease Sen15, tRNA-splicing endonuclease subunit Sen15
Supplier: United States Biological
Supplier-Nr: C5071-19C

Properties

MW: 20,9 kD
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
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