ASCL1 PrEST Antigen

ASCL1 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST95383.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: Transcription factor that plays a key role in neuronal differentiation: acts as... more
Product information "ASCL1 PrEST Antigen"
Protein function: Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways. Directly binds the E box motif (5'-CANNTG-3') on promoters and promotes transcription of neuronal genes. The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro. Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Involved in the regulation of neuroendocrine cell development in the glandular stomach. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: ASH-1, hASH1, bHLHa46, Achaete-scute homolog 1, Class A basic helix-loop-helix protein 46
Supplier: Atlas Antibodies
Supplier-Nr: APrEST95383

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "ASCL1 PrEST Antigen"
Write a review
or to review a product.
Viewed