AIP, Recombinant, Human, aa1-330, His-tag (aryl hydrocarbon receptor interacting protein, ARA9, FKBP

Aryl hydrocarbon receptor (AHR) interacting protein, also known as AIP, may play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. It is a Cellular negative regulator of the hepatitis B virus (HBV) X protein. Also, AIP is a ubiquitously expressed protein, binds to HSP 90 and AHR through a highly conserved carboxy-terminal tetraticopeptide repeat domain. Purified by using conventional chromatography techniques. Recombinant protein corresponding to aa1-330 of human AIP, fused to His-tag at the N-terminal, expressed in E. coli (AAI04828). , Amino Acid Sequence:, MGSSHHHHHH SSGLVPRGSH MADIIARLRE DGIQKRVIQE GRGELPDFQD GTKATFHYRT LHSDDEGTVL DDSRARGKPM ELIIGKKFKL PVWETIVCTM REGEIAQFLC DIKHVVLYPL VAKSLRNIAV GKDPLEGQRH CCGVAQMREH SSLGHADLDA LQQNPQPLIF HMEMLKVESP , GTYQQDPWAM TDEEKAKAVP LIHQEGNRLY REGHVKEAAA KYYDAIACLK NLQMKEQPGS PEWIQLDKQI TPLLLNYCQC KLVVEEYYEV LDHCSSILNK YDDNVKAYFK RGKAHAAVWN AQEAQADFAK VLELDPALAP VVSRELRALE ARIRQKDEED KARFRGIFSH, Molecular Weight: ~39.8kD (350aa), confirmed by MALDI-TOF, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.