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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay27435-500 | 500 µg | - |
6 - 10 business days* |
84.00€
|
|||
Cay27435-1 | 1 mg | - |
6 - 10 business days* |
155.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3. It reduces IL-1beta and IL-18 secretion in... more
Product information "Z-YVAD-CMK (trifluoroacetate salt)"
Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3. It reduces IL-1beta and IL-18 secretion in isolated mouse peritoneal macrophages stimulated by cholesterol-treated recombinant pneumolysin protein (rPLY) when used at a concentration of 30 µM. Z-YVAD-CMK reduces caspase-3 activation by the EGF-like domain of tenascin-C in detached human smooth muscle cells (hSMCs) in vitro. It also decreases cell death induced by the EGF-like domain of tenascin-C by 50% when used at a concentration of 100 µM in hSMCs and completely inhibits cell death at concentrations ranging from 200 to 400 µM.Formal Name: N-[(phenylmethoxy)carbonyl]-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-L-alaninamide, trifluoroacetate salt. Synonyms: Benxyloxycarbonyl-Tyr-Val-Ala-Asp-Chloromethylketone, Caspase-1 Inhibitor IV. Molecular Formula: C30H37ClN4O9 . XCF3COOH. Formula Weight: 633.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 1 mg/ml. SMILES: O=C([C@H](C)NC([C@H](C(C)C)NC([C@H](CC1=CC=C(O)C=C1)NC(OCC2=CC=CC=C2)=O)=O)=O)N[C@H](C(CCl)=O)CC(O)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C30H37ClN4O9.C2HF3O2/c1-17(2)26(29(42)32-18(3)27(40)33-22(14-25(38)39)24(37)15-31)35-28(41)23(13-19-9-11-21(36)12-10-19)34-30(43)44-16-20-7-5-4-6-8-20,3-2(4,5)1(6)7/h4-12,17-18,22-23,26,36H,13-16H2,1-3H3,(H,32,42)(H,33,40)(H,34,43)(H,35,41)(H,38,39),(H,6,7)/t18-,22-,23-,26-,/m0./s1. InChi Key: VIEXXRMVRHEMFV-NWFMSPOZSA-N.
Keywords: | Benxyloxycarbonyl-Tyr-Val-Ala-Asp-Chloromethylketone, Caspase-1 Inhibitor IV, N-[(phenylmethoxy)carbonyl]-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-L-alaninamide, trifluoroacetate salt |
Supplier: | Cayman Chemical |
Supplier-Nr: | 27435 |
Properties
Application: | Caspase-1 / caspase-3 inhibitor |
Conjugate: | No |
MW: | 633.1 D |
Formula: | C30H37ClN4O9 . XCF3COOH |
Purity: | >95% |
Format: | Solid |
Database Information
KEGG ID : | K01370 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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