Z-AEVD-FMK

Z-AEVD-FMK
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay14987-500 500 µg -

6 - 10 business days*

92.00€
Cay14987-1 1 mg -

6 - 10 business days*

175.00€
Cay14987-5 5 mg -

6 - 10 business days*

764.00€
 
Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases. At 10 µM, it can... more
Product information "Z-AEVD-FMK"
Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases. At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.Formal Name: methyl-14S-(2-fluoroacetyl)-11S-isopropyl-8S-(3-methoxy-3-oxopropyl)-5S-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate. CAS Number: 1135688-47-9. Synonyms: Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone. Molecular Formula: C28H39FN4O10. Formula Weight: 610.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 10 mg/ml*. SMILES: C[C@H](NC(OCC1=CC=CC=C1)=O)C(N[C@@H](CCC(OC)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(OC)=O)C(CF)=O)=O)=O)=O. InChi Code: InChI=1S/C28H39FN4O10/c1-16(2)24(27(39)32-20(21(34)14-29)13-23(36)42-5)33-26(38)19(11-12-22(35)41-4)31-25(37)17(3)30-28(40)43-15-18-9-7-6-8-10-18/h6-10,16-17,19-20,24H,11-15H2,1-5H3,(H,30,40)(H,31,37)(H,32,39)(H,33,38)/t17-,19-,20-,24-/m0/s1. InChi Key: CHZRBQFKZDGMTP-CDSYHYPYSA-N.
Keywords: Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone, methyl-14S-(2-fluoroacetyl)-11S-isopropyl-8S-(3-methoxy-3-oxopropyl)-5S-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate
Supplier: Cayman Chemical
Supplier-Nr: 14987

Properties

Application: Irreversible caspase-10 inhibitor
Conjugate: No
MW: 610.6 D
Formula: C28H39FN4O10
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 1135688-47-9| Matching products
KEGG ID : K04400 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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