Ac-VEID-CHO (trifluoroacetate salt)

Ac-VEID-CHO (trifluoroacetate salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay27437-5 5 mg -

6 - 10 business days*

205.00€
 
Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM). It is selective for caspase-6 over... more
Product information "Ac-VEID-CHO (trifluoroacetate salt)"
Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM). It is selective for caspase-6 over caspase-7 (IC50 = 162.1 nM) but can also inhibit caspase-3 (IC50 = 13.6 nM). Ac-VEID-CHO (100 µM) inhibits ricin-induced caspase-6-, but not caspase-3-, like activity in U937 cells. It also inhibits caspase-6-like activity in Norway spruce cell extracts when used at a concentration of 2 µM, as well as in staurosporine-treated SKNAS neuroblastoma cells with an IC50 value of 0.49 µM.Formal Name: (4S,7S,10S,13S)-10-((S)-sec-butyl)-7-(2-carboxyethyl)-13-formyl-4-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid, trifluoroacetate salt. Synonyms: Ac-Val-Glu-Ile-Asp-CHO. Molecular Formula: C22H36N4O9 . XCF3COOH. Formula Weight: 500.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: OC(C[C@H](NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@H](C(C)C)NC(C)=O)=O)CCC(O)=O)=O)=O)C=O)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C22H36N4O9.C2HF3O2/c1-6-12(4)19(22(35)24-14(10-27)9-17(31)32)26-20(33)15(7-8-16(29)30)25-21(34)18(11(2)3)23-13(5)28,3-2(4,5)1(6)7/h10-12,14-15,18-19H,6-9H2,1-5H3,(H,23,28)(H,24,35)(H,25,34)(H,26,33)(H,29,30)(H,31,32),(H,6,7)/t12-,14-,15-,18-,19-,/m0./s1. InChi Key: DMUVMYXFMMONRW-NVOIZEPQSA-N.
Keywords: Ac-Val-Glu-Ile-Asp-CHO, (4S,7S,10S,13S)-10-((S)-sec-butyl)-7-(2-carboxyethyl)-13-formyl-4-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid, trifluoroacetate salt
Supplier: Cayman Chemical
Supplier-Nr: 27437

Properties

Application: Caspase-6 inhibitor
Conjugate: No
MW: 500.5 D
Formula: C22H36N4O9 . XCF3COOH
Purity: >95%
Format: Solid

Database Information

KEGG ID : K04396 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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