Substrates and Inhibitors

2 from 35 pages
No results were found for the filter!
NEW
NucView(R) 405 Caspase-3 Substrate, 1 mM in 1X PBS
NucView(R) 405 Caspase-3 Substrate, 1 mM in 1X PBS

Item number: BOT-10407

NucView(R) 405 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry. In contrast to other fluorogenic caspase substrates or fluorescent caspase inhibitor based (FLICA) assays, NucView(R)...
From 111.00€ *
Review
NEW
NucView(R) 530 Caspase-3 Substrate, 1 mM in 1X PBS
NucView(R) 530 Caspase-3 Substrate, 1 mM in 1X PBS

Item number: BOT-10408

NucView(R) 530 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry. In contrast to other fluorogenic caspase substrates or fluorescent caspase inhibitor based (FLICA) assays, NucView(R)...
From 111.00€ *
Review
Ac-DEVD-aminoluciferin
Ac-DEVD-aminoluciferin

Item number: ABD-13210

Molecular weight: 779.79. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Ac-DEVD-aminoluciferin is a luminogenic substrate that measures caspase-3 and -7 activities in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
Application: Luminogenic caspase-3/-7 substrate
MW: 779.79 D
120.00€ *
Review
Z-LETD-aminoluciferin
Z-LETD-aminoluciferin

Item number: ABD-13212

Molecular weight: 871.93. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Z-LETD-aminoluciferin is a luminogenic substrate that measures caspase-8 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
Application: Luminogenic caspase-8 substrate
MW: 871.93 D
868.00€ *
Review
Z-LEHD-aminoluciferin
Z-LEHD-aminoluciferin

Item number: ABD-13213

Molecular weight: 1021.99. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Z-LEHD-aminoluciferin is a luminogenic substrate that measures caspase-9 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
Application: Luminogenic caspase-9 substrate
MW: 1021.99 D
868.00€ *
Review
Z-IETD-aminoluciferin
Z-IETD-aminoluciferin

Item number: ABD-13214

Molecular weight: 871.93. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Z-IETD-aminoluciferin is a luminogenic substrate that measures caspase-6 and granzyme B activities in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of...
Application: Luminogenic caspase-6/granzyme B substrate
MW: 871.93 D
1,117.00€ *
Review
Z-VDVAD-aminoluciferin
Z-VDVAD-aminoluciferin

Item number: ABD-13215

Molecular weight: 912.99. Extinction coefficient (cm^-1 M^-1): 18000 Excitation (nm): 362. Emission (nm): 499. Z-VDVAD-aminoluciferin is a luminogenic substrate that measures caspase-2 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
Application: Luminogenic caspase-2 substrate
MW: 912.99 D
1,810.00€ *
Review
Z-VEID-aminoluciferin
Z-VEID-aminoluciferin

Item number: ABD-13216

Molecular weight: 869.96. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Z-VEID-aminoluciferin is a luminogenic substrate that measures caspase-6 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
Application: Luminogenic caspase-6 substrate
MW: 869.96 D
1,117.00€ *
Review
Z-ATAD-aminoluciferin
Z-ATAD-aminoluciferin

Item number: ABD-13217

Molecular weight: 771.82. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Z-ATAD-aminoluciferin is a luminogenic substrate that measures caspase-12 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
Application: Luminogenic caspase-12 substrate
MW: 771.82 D
1,117.00€ *
Review
Tat-Gap 19 (trifluoroacetate salt)
Tat-Gap 19 (trifluoroacetate salt)

Item number: Cay36729-1

Tat-Gap 19 is a peptide inhibitor of connexin43 (Cx43) hemichannels. It is composed of the HIV-1 Tat protein transduction domain linked to a nine-amino acid peptide corresponding to residues 128-136 of Cx43. Tat-Gap 19 (10 µM) inhibits glutamate-induced ATP release, a marker of Cx43 hemichannel activity, in primary...
Keywords: L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-glutami...
Application: Cx43 (GJA1) hemichannel peptide inhibitor
MW: 2703.3 D
From 155.00€ *
Review
RS Repeat Peptide (trifluoroacetate salt)
RS Repeat Peptide (trifluoroacetate salt)

Item number: Cay37498-1

RS repeat peptide is a serine/arginine-rich peptide substrate for CDC-like kinase 1 (Clk1). It has been used to identify inhibitors of Clk1 with anticancer activity. Formal name:...
Keywords: glycyl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-argin...
Application: CDC-like kinase 1 (Clk1) peptide substrate
MW: 1934.1 D
From 53.00€ *
Review
TF2-HQKLVFFAK-TQ2 [TF2-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-TQ2]
TF2-HQKLVFFAK-TQ2...

Item number: ABD-13206

Extinction coefficient (cm^-1 M^-1): 80000. Excitation (nm): 500. Emission (nm): 522, TF2-HQKLVFFAK-TQ2 [TF2-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-TQ2] has much stronger fluoresce upon protease cleavage than the commonly used FRET peptide MCA-HQKLVFFA (K-DNP), a secretase FRET peptide substrate. In addition, the...
Application: Fluorogenic alpha-secretase substrate
868.00€ *
Review
2 from 35 pages