Z-VAD(OMe)-FMK

Z-VAD(OMe)-FMK
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay14463-1 1 mg -

6 - 10 business days*

134.00€
Cay14463-5 5 mg -

6 - 10 business days*

571.00€
 
Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases.... more
Product information "Z-VAD(OMe)-FMK"
Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases. Through this action, it inhibits cleavage of poly(ADP-ribose) polymerase, preventing apoptosis when used at 10-50 µM. It also blocks caspase-mediated apoptosis in vivo. Z-VAD(OMe)-FMK effectively prevents caspase action in inflammasomes.Formal Name: N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide. CAS Number: 187389-52-2. Synonyms: Z-Val-Ala-Asp-(OMe)-Fluoromethyl Ketone. Molecular Formula: C22H30FN3O7. Formula Weight: 467.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 5 mg/ml. SMILES: O=C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@H](C(CF)=O)CC(OC)=O)=O)=O)OCC1=CC=CC=C1. InChi Code: InChI=1S/C22H30FN3O7/c1-13(2)19(26-22(31)33-12-15-8-6-5-7-9-15)21(30)24-14(3)20(29)25-16(17(27)11-23)10-18(28)32-4/h5-9,13-14,16,19H,10-12H2,1-4H3,(H,24,30)(H,25,29)(H,26,31)/t14-,16-,19-/m0/s1. InChi Key: MIFGOLAMNLSLGH-QOKNQOGYSA-N.
Keywords: Z-Val-Ala-Asp-(OMe)-Fluoromethyl Ketone, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide
Supplier: Cayman Chemical
Supplier-Nr: 14463

Properties

Application: Caspase inhibitor
Conjugate: No
MW: 467.5 D
Formula: C22H30FN3O7
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 187389-52-2| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Z-VAD(OMe)-FMK"
Write a review
or to review a product.
Viewed