RSVA Peptide Pool

Pool of 72 overlapping peptides derived from a peptide scan (15mers with 11 aa overlap) through Major surface glycoprotein G (UniProt ID: P03423) of Human respiratory syncytial virus A (strain A2) One unit allows the stimulation of 2,5 x 10^8 cells. Protein function: [Isoform Membrane-bound glycoprotein G]: Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection (PubMed:3655746, PubMed:10400758, PubMed:10864656). Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection (PubMed:26658574, PubMed:11477410, PubMed:26107373). Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (Probable). [The UniProt Consortium]