PAR2 (1-6) (mouse, rat)

PAR2 (1-6) (mouse, rat)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay27125-1 1 mg -

6 - 10 business days*

60.00€
Cay27125-5 5 mg -

6 - 10 business days*

259.00€
Cay27125-10 10 mg -

6 - 10 business days*

457.00€
Cay27125-25 25 mg -

6 - 10 business days*

998.00€
 
PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that... more
Product information "PAR2 (1-6) (mouse, rat)"
PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces relaxation in precontracted rat arteries in a concentration-dependent manner, an effect that can be reduced by the nitric oxide synthase inhibitor L-NNA (Cay-80220). It inhibits keratinocyte growth in the presence and absence of growth factors. PAR2 (1-6) inhibits LPS-induced pulmonary neutrophil influx and increases in matrix metalloproteinase-2 (MMP-2) activity in mice.Formal Name: L-seryl-L-leucyl-L-isoleucylglycyl-L-arginyl-L-leucine. CAS Number: 164081-25-8. Synonyms: SLIGRL. Molecular Formula: C29H55N9O8. Formula Weight: 657.8. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: [H]N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@]([C@H](CC)C)([H])C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O. InChi Code: InChI=1S/C29H55N9O8/c1-7-17(6)23(38-26(43)20(11-15(2)3)36-24(41)18(30)14-39)27(44)34-13-22(40)35-19(9-8-10-33-29(31)32)25(42)37-21(28(45)46)12-16(4)5/h15-21,23,39H,7-14,30H2,1-6H3,(H,34,44)(H,35,40)(H,36,41)(H,37,42)(H,38,43)(H,45,46)(H4,31,32,33)/t17-,18-,19-,20-,21-,23-/m0/s1. InChi Key: CNOKQOBEMGIIAH-JYAZKYGWSA-N.
Keywords: SLIGRL, L-seryl-L-leucyl-L-isoleucylglycyl-L-arginyl-L-leucine
Supplier: Cayman Chemical
Supplier-Nr: 27125

Properties

Application: Synthetic peptide PAR2 agonist
Conjugate: No
MW: 657.8 D
Formula: C29H55N9O8
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 164081-25-8| Matching products
KEGG ID : K04234 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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