Onychocin B

Onychocin B is a cyclic tetrapeptide originally isolated from Onychocola sclerotica that has calcium channel inhibitory activity. It inhibits the voltage-gated calcium (Cav) channel Cav1.2 with an IC50 value of 7.1 µM.Formal Name: 6S,12R-dibenzyl-3S-((S)-sec-butyl)-9S-isopropyl-1,7-dimethyl-1,4,7,10-tetraazacyclododecane-2,5,8,11-tetraone. Molecular Formula: C31H42N4O4. Formula Weight: 534.7. Purity: >95%. Formulation: (Request formulation change), A solid. SMILES: O=C([C@H](C(C)C)NC([C@@H](CC1=CC=CC=C1)N(C)C2=O)=O)N([C@@H](CC3=CC=CC=C3)C(N[C@@]2([H])[C@@H](C)CC)=O)C. InChi Code: InChI=1S/C31H42N4O4/c1-7-21(4)27-31(39)35(6)24(18-22-14-10-8-11-15-22)28(36)32-26(20(2)3)30(38)34(5)25(29(37)33-27)19-23-16-12-9-13-17-23/h8-17,20-21,24-27H,7,18-19H2,1-6H3,(H,32,36)(H,33,37)/t21-,24+,25-,26-,27-/m0/s1. InChi Key: KZGZTOMXQSOTKE-KOMOQGMXSA-N. Origin: Fungi/Aspergillus sp..