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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay11189-5 | 5 mg | - |
6 - 10 business days* |
115.00€
|
|||
Cay11189-25 | 25 mg | - |
6 - 10 business days* |
508.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
N-acetyl-Pro-Gly-Pro (N-acetyl-PGP) is a tripeptide that functions as a neutrophil... more
Product information "N-acetyl-Pro-Gly-Pro Peptide"
N-acetyl-Pro-Gly-Pro (N-acetyl-PGP) is a tripeptide that functions as a neutrophil chemoattractant. N-acetyl-PGP and PGP induce the recruitment of neutrophils (PMN) through stimulation of chemokine CXC receptors. N-acetyl-PGP is derived from the breakdown of extracellular matrix (ECM) and shares sequence and structural homology with a domain on alpha chemokines. Breakdown of collagen in the lungs leading to the production of PGP metabolites. Such metabolites have been seen in substantially higher concentrations from bronchoalveolar lavage (BAL) samples of individuals with chronic obstructive pulmonary disease (COPD) and cystic fibrosis relative to control patients. The increased production of the pro-inflammatory PGP exacerabates the inflammatory process leads to increased neutrophil recruitment in airway inflammation. These data suggest that N-acetyl-PGP or PGP may be useful biomarkers and potential therapeutic targets for neutrophilic inflammatory diseases.Synonyms: N-acetyl-PGP. Formula Weight: 311.3. Purity: >95% by HPLC. Amino Acids: N-terminal acetylated-PGP. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml.
Keywords: | N-acetyl-PGP |
Supplier: | Cayman Chemical |
Supplier-Nr: | 11189 |
Properties
Application: | Neutrophil chemoattractant |
Conjugate: | No |
MW: | 311.3 D |
Purity: | >95% by HPLC |
Format: | Solid |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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