MeOSuc-AAPV-pNA

MeOSuc-AAPV-pNA
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay17601-5 5 mg -

6 - 10 business days*

43.00€
Cay17601-10 10 mg -

6 - 10 business days*

77.00€
Cay17601-25 25 mg -

6 - 10 business days*

146.00€
Cay17601-50 50 mg -

6 - 10 business days*

164.00€
 
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades... more
Product information "MeOSuc-AAPV-pNA"
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.Formal Name: N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide. CAS Number: 70967-90-7. Molecular Formula: C27H38N6O9. Formula Weight: 590.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 5 mg/ml, PBS (pH 7.2): Slightly Soluble. lambdamax: 210, 224, 315 nm. SMILES: COC(CCC(N[C@@H](C)C(N[C@@H](C)C(N1CCC[C@H]1C(N[C@H](C(NC2=CC=C([N+]([O-])=O)C=C2)=O)C(C)C)=O)=O)=O)=O)=O. InChi Code: InChI=1S/C27H38N6O9/c1-15(2)23(26(38)30-18-8-10-19(11-9-18)33(40)41)31-25(37)20-7-6-14-32(20)27(39)17(4)29-24(36)16(3)28-21(34)12-13-22(35)42-5/h8-11,15-17,20,23H,6-7,12-14H2,1-5H3,(H,28,34)(H,29,36)(H,30,38)(H,31,37)/t16-,17-,20-,23-/m0/s1. InChi Key: VLVGCNNWNUERRZ-OSAZLGQLSA-N.
Keywords: N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide
Supplier: Cayman Chemical
Supplier-Nr: 17601

Properties

Application: Neutrophil elastase & PR3 substrate
Conjugate: No
MW: 590.6 D
Formula: C27H38N6O9
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 70967-90-7| Matching products
KEGG ID : K01327 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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