Malformin C

Malformin C
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay21613-500 500 µg -

approx. 1-3 business days

232.00€
Cay21613-1 1 mg -

1 - 10 business days

394.00€
 
Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties,... more
Product information "Malformin C"
Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin (Cay-13877) to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates colchicine-induced M phase arrest in Jurkat cells (IC50 = 24 nM). Malformin C inhibits cell growth dose-dependently in Colon 38 and HCT 115 cancer cells (IC50s = 0.27 and 0.18 µM, respectively) but has a low therapeutic index against cancer xenografts when tested in mice.
Keywords: Malformin B1b, cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1->2)-disulfide
Supplier: Cayman Chemical
Supplier-Nr: 21613-1

Properties

Application: Antibacterial
Conjugate: No
MW: 529.7 D
Formula: C23H39N5O5S2
Purity: >95%
Format: Solid

Database Information

CAS : 59926-78-2| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301, H311, H330
P Phrases: P260, P264, P270, P271, P280, P284, P312, P320, P321, P330, P301+P310, P302+P352, P304+P340, P361+P364, P405, P403+P233, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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