Malformin C

Malformin C
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay21613-500 500 µg -

6 - 10 business days*

304.00€
Cay21613-1 1 mg -

6 - 10 business days*

514.00€
 
Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties,... more
Product information "Malformin C"
Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin (Cay-13877) to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates colchicine-induced M phase arrest in Jurkat cells (IC50 = 24 nM). Malformin C inhibits cell growth dose-dependently in Colon 38 and HCT 115 cancer cells (IC50s = 0.27 and 0.18 µM, respectively) but has a low therapeutic index against cancer xenografts when tested in mice.Formal Name: cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1->2)-disulfide. CAS Number: 59926-78-2. Synonyms: Malformin B1b. Molecular Formula: C23H39N5O5S2. Formula Weight: 529.7. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Soluble, DMSO: Soluble, Ethanol: Soluble, Methanol: Soluble. SMILES: O=C1[C@H](CC(C)C)NC([C@@H](CC(C)C)NC([C@H](C(C)C)NC([C@@H]2NC([C@@H](CSSC2)N1)=O)=O)=O)=O. InChi Code: InChI=1S/C23H39N5O5S2/c1-11(2)7-14-20(30)26-16-9-34-35-10-17(27-21(16)31)22(32)28-18(13(5)6)23(33)25-15(8-12(3)4)19(29)24-14/h11-18H,7-10H2,1-6H3,(H,24,29)(H,25,33)(H,26,30)(H,27,31)(H,28,32)/t14-,15+,16+,17+,18-/m0/s1. InChi Key: TZODYIWCRGWHQB-TZNCUMHOSA-N. Origin: Synthetic.
Keywords: Malformin B1b, cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1->2)-disulfide
Supplier: Cayman Chemical
Supplier-Nr: 21613

Properties

Application: Antibacterial
Conjugate: No
MW: 529.7 D
Formula: C23H39N5O5S2
Purity: >95%
Format: Solid

Database Information

CAS : 59926-78-2| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301, H311, H330
P Phrases: P260, P264, P270, P271, P280, P284, P301+310, P302+352, P304+340, P310, P312, P320, P321, P330, P361+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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