Iberiotoxin (trifluoroacetate salt)

Iberiotoxin (trifluoroacetate salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay14608-100 100 µg -

6 - 10 business days*

448.00€
 
Iberiotoxin, a peptide purified from venom of the scorpion B. tamulus, is a selective blocker of... more
Product information "Iberiotoxin (trifluoroacetate salt)"
Iberiotoxin, a peptide purified from venom of the scorpion B. tamulus, is a selective blocker of large-conductance calcium-activated potassium channels (KCa1.1/BKCa). In single channel recordings, iberiotoxin can reversibly block outward currents mediated by KCa1.1 in excised membrane patches from bovine aortic smooth muscle with an IC50 value of 250 pM. It is also a noncompetitive, partial inhibitor of charybdotoxin binding in bovine aortic sarcolemmal membrane vesicles (Ki = 250 pM).CAS Number: 182897-30-9. Formula Weight: 4230.9. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: Soluble. SMILES: [H]N(C(C1CCC(N1)=O)=O)[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@H](C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(NCC(N[C@@H](C(C)C)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCN)C2=O)=O)=O)=O)CC(O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)CC(O)=O)=O)=O)CSSC[C@H](N4)C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)=O)CC6=CNC7=C6C=CC=C7)=O)CSSC[C@H](N8)C(N[C@@H](CCCNC(N)=N)C4=O)=O)=O)=O)=O)=O)=O)=O)CSSC[C@H](N2)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C8=O)=O)=O)=O)CCSC)=O)=O)CC(O)=O)=O)=O)CC(O)=O)=O)=O)CC9=CC=CC=C9.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C179H274N50O55S7.C2HF3O2/c1-87(2)65-111-155(261)208-112(66-93-33-15-13-16-34-93)146(252)195-77-133(239)225-139(88(3)4)172(278)213-117(71-136(244)245)158(264)199-100(44-31-62-190-178(186)187)144(250)193-75-131(237)198-102(40-22-27-58-181)148(254)219-124-82-287-290-85-127(223-160(266)118(72-137(246)247)214-173(279)140(89(5)6)226-162(268)119(73-138(248)249)215-176(282)143(92(11)233)229-161(267)114(67-94-35-17-14-18-36-94)209-153(259)107-51-54-130(236)196-107)171(277)217-122(80-232)165(271)227-141(90(7)8)174(280)218-120(78-230)163(269)201-103(41-23-28-59-182)149(255)204-108(52-55-134(240)241)154(260)222-126-84-288-286-81-123(220-151(257)105(43-25-30-61-184)200-147(253)101(39-21-26-57-180)197-132(238)76-194-145(251)109(56-64-285-12)205-167(124)273)166(272)203-106(45-32-63-191-179(188)189)152(258)221-125(169(275)210-113(68-95-46-48-97(234)49-47-95)156(262)206-110(177(283)284)50-53-129(185)235)83-289-291-86-128(168(274)202-104(42-24-29-60-183)150(256)212-116(70-135(242)243)159(265)207-111)224-175(281)142(91(9)10)228-164(270)121(79-231)216-157(263)115(211-170(126)276)69-96-74-192-99-38-20-19-37-98(96)99,3-2(4,5)1(6)7/h13-20,33-38,46-49,74,87-92,100-128,139-143,192,230-234H,21-32,39-45,50-73,75-86,180-184H2,1-12H3,(H2,185,235)(H,193,250)(H,194,251)(H,195,252)(H,196,236)(H,197,238)(H,198,237)(H,199,264)(H,200,253)(H,201,269)(H,202,274)(H,203,272)(H,204,255)(H,205,273)(H,206,262)(H,207,265)(H,208,261)(H,209,259)(H,210,275)(H,211,276)(H,212,256)(H,213,278)(H,214,279)(H,215,282)(H,216,263)(H,217,277)(H,218,280)(H,219,254)(H,220,257)(H,221,258)(H,222,260)(H,223,266)(H,224,281)(H,225,239)(H,226,268)(H,227,271)(H,228,270)(H,229,267)(H,240,241)(H,242,243)(H,244,245)(H,246,247)(H,248,249)(H,283,284)(H4,186,187,190)(H4,188,189,191),(H,6,7)/t92-,100+,101+,102+,103+,104+,105+,106+,107?,108+,109+,110+,111+,112+,113+,114+,115+,116+,117+,118+,119+,120+,121+,122+,123+,124+,125+,126+,127+,128+,139+,140+,141+,142+,143+,/m1./s1. InChi Key: ZDGJIMQFDSPUJP-XYHSBZLHSA-N.
Keywords: 4-L-aspartic acid-6-L-aspartic acid-8-L-serine-9-L-valine-18-L-lysine-19-L-aspartic acid-21-L-phenylalanine-22-glycine-23-L-valine-24-L-aspartic acid-30-glycine-37-L-glutamine-charybdotoxin
Supplier: Cayman Chemical
Supplier-Nr: 14608

Properties

Application: BKCa blocker
Conjugate: No
MW: 4230.9 D
Purity: >95%
Format: Solid

Database Information

CAS : 182897-30-9| Matching products
KEGG ID : K04936 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H300, H310, H330
P Phrases: P260, P262, P264, P270, P271, P280, P284, P320, P321, P330, P301+P310, P302+P352, P304+P340, P361+P364, P405, P403+P233, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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